If you’re reading this chances are you’ve probably already learned that Ctrl + F5 in Firefox on Mac OSX opens the screen reader. Typically in most browsers Firefox, Chrome, Internet Explorer etcetera, Ctrl + F5 hard refreshes the page. Meaning that the browser does not read any of the information on the page from cache, instead it downloads everything fresh. The correct command to do a hard refresh in Firefox on a page (force the page to reload all data) is “Cmd (Apple) + Shift + R”. This only works on Firefox, not in Safari.
If you need to disable the screen reader press Ctrl + F5 again and it should turn off.
I learned this while working on a client for our Fort Myers Business IT Tech Support Company